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| Product Name | SS-31 |
| Other Name | Elamipretide |
| CAS NO. | 736992-21-5 |
| Appearance | White freeze-dried powder |
| Purity | 98% HPLC |
| Application | Research peptides |
| Shelf Life | 24 Months |
| Storage | Store at a temperature of 2-8 degrees, protected from light. |
What is SS-31?
Elamipretide (SS-31) is a small peptide that can reach inside the mitochondria and affect mitochondrial function maintenance. Elamipretide belongs to a family of cell-penetrating peptides that target and accumulate at the inner mitochondrial membrane. Inside the mitochondria, elamipretide binds to cardiolipin, an essential component of the inner mitochondrial membrane, and restores the mitochondria.
Given the effects of elamipretide on mitochondrial function and maintenance, treatment with elamipretide is under investigation to determine its benefits on human health. Recently, scientists have discovered at least four excellent benefits that can potentially make elamipretide a viable treatment option for a wide variety of conditions.
In diabetes research, SS-31 can improve mitochondrial dysfunction related to diabetes and has potential value in the treatment of diabetes and its complications. For sepsis, SS-31 can reduce vascular permeability in septic rats. The protective effect is related to the inhibition of oxidative stress, providing a new strategy for clinical treatment.
SS-31 Benefits
Elamipretide Can Treat Mitochondrial Dysfunction
Elamipretide Can Prevent Cardiovascular Disease Risk
Reduces internal inflammation
Elamipretide Can Improve Cognitive Impairment
Elamipretide Can Enhance Physical Endurance
Retatrutide -developed by pharmaceutical giant Eli Lilly and alternatively known as GGG Tri-agonist, GLP-1/GIP/glucagon tri-agonist, or LY3437943-is an injectable breakthrough poised for FDA approval, with significant potential to treat obesity and diabetes. While it shares similarities with established weight loss therapies like tirzepatide and semaglutide, retatrutide delivers enhanced efficacy. When paired with balanced nutrition, consistent physical activity, and healthy lifestyle adjustments, it not only amplifies weight loss results but also addresses obesity-related comorbidities such as diabetes and hypertension (high blood pressure).
What sets retatrutide apart from other weight loss medications is its superior effectiveness, driven by three key therapeutic mechanisms:
**Gastric Inhibitory Polypeptide Receptor (GIPR) Agonism: By activating GIP receptors, retatrutide strengthens appetite control, blocks fat storage, reduces caloric intake, and boosts energy expenditure.
**Glucagon-Like Peptide 1 Receptor (GLP-1R) Agonism: It supports weight reduction by improving glycemic control-stimulating pancreatic insulin secretion while curbing the release of glucagon, a hormone that elevates blood sugar levels.
**Glucagon Receptor (GR) Agonism**: Retatrutide further regulates blood glucose by suppressing glucagon release, diminishes food cravings, and increases energy burn, all of which contribute to meaningful weight loss.
| Item | Information |
|---|---|
| Product Name | Retatrutide |
| Trade Name | LY-3437943 |
| CAS No. | 2381089-83-2 |
| Molecular Formula | C₂₂₁H₃₄₂N₄₆O₆₈ |
| Molecular Weight | 4731.33 g/mol |
| Peptide Sequence | Tyr-{Aib}-Gln-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Ile-{α-Me-Leu}-Leu-Asp-Lys-{diacid-C20-gamma-Glu-(AEEA)-Lys}-Ala-Gln-{Aib}-Ala-Phe-Ile-Glu-Tyr-Leu-Leu-Glu-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH₂ |
| Appearance | White Lyophilized powder |
| Reconstitution | Required |
| Storage (Post-reconstitution) | Store at 2°C - 8°C |
BENEFITS OF GLP-1 AGONISTS
Slows gastric emptying to prolong feelings of fullness
Suppresses excessive hepatic glucose production (prevents the liver from overproducing sugar)
Stimulates pancreatic insulin secretion in response to elevated blood glucose levels
Aids in glycemic control and blood sugar regulation
Alleviates hyperglycemia, particularly postprandial (after-meal) spikes
Reduces fasting insulin concentrations and fasting blood glucose levels
Lowers hemoglobin A1c (HbA1c) to improve long-term glycemic outcomes
Curbs appetite and reduces caloric consumption, while counteracting weight gain
Demonstrates efficacy in lowering triglyceride levels and mitigating oxidative stress associated with high LDL ("bad" cholesterol)
Promotes weight loss in obese patients when administered at higher dosages
Decreases leptin levels and enhances leptin sensitivity (improving the body's ability to regulate hunger and metabolism)
Facilitates the browning of white adipose tissue (converts energy-storing white fat to energy-burning brown fat)
Company profile
Guangsheng Technology Co., Ltd. We strive for survival, innovation and development through quality. We adhere to the business philosophy of honesty and trustworthiness, uphold the quality policy of "all based on quality standards, with customer satisfaction as the goal, pursuing novelty and people-oriented quality", and continuously improve and perfect ourselves. We are the developers and leaders of green active materials. Professional product production, product transportation and professional team services have enabled us to gain a good reputation worldwide.
service
1. We supply Peptides, APIs & Intermediates and so on to satisfy your needs;
2. We will reply you for your inquiry in 24 hours;
3. Strictly on selecting raw materials . Our Q&C team will inspect every product quality strictly before delivery;
4. Reasonable & competitive price, fast lead time ;
5. After delivery, we will track the products for you once every two days, until you get the products. When you got the goods, if you have any questions about the problem, contact with us, we will offer the solve way for you ;
6. 100% safe delivery, guaranteed delivery .
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